ATC PROGRAM
Sunday, June 1, 2008Sunday | Monday | Tuesday | Wednesday |
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Sunrise Symposia7:00 am – 8:15 am |
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Renal Transplant Clinical PathologyChairs: Mark D. Stegall,MD,Mayo Clinic Rochester, Rochester,MN and Anthony J. Demetris,MD, University of Pittsburgh, Pittsburgh, PA*NOTE: This session is a special interactive session with audience response participation |
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| 7:00 am – 7:20 am | Case Presentation Fernando G. Cosio, MD Mayo Clinic Rochester, Rochester, MN |
| 7:20 am – 7:40 am | Case Discussion Robert B. Colvin, MD Massachusetts General Hospital, Boston,MA |
| 7:40 am – 8:00 am | Endothelial Cell Injury and Antibody Philip Halloran, MD University of Alberta, Edmonton, Canada |
| 8:00 am – 8:15 am | Audience Response Participation |
mTOR and Vascular Biology: Discovery to TranslationChair: David M. Briscoe, MD, Children's Hospital of Boston, Boston, MA and Marie-Josee Hebert, MD, University of Montreal, Montreal, Canada |
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| 7:00 am – 7:25 am | mTOR Complexes and Intracellular Signaling Via the AGC Kinase and PKC Bing Su, PhD Yale University, New Haven, CT |
| 7:25 am – 7:50 am | mTOR/Akt Interactions in Vascular Biology Laura Benjamin, PhD Beth Israel Deaconess Medical Center, Boston, MA |
| 7:50 am – 8:15 am | mTOR and the Development of Allograft Pathology David M. Briscoe,MD Children's Hospital of Boston, Boston, MA |
Pancreas Alone Vs. Islet Transplantation – Current ControversiesChairs: Steven Paraskevas, MD, PhD, McGill University Health Centre, Montreal, Canada and Patrick Dean, MD, Mayo Clinic Rochester, Rochester, MN*NOTE: This session is a special interactive session with audience response participation |
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| 7:00 am – 7:20 am | Islets Paolo Fiorina, MD Boston Children's Hospital, Boston, MA |
| 7:20 am – 7:40 am | Pancreas Raja Kandaswamy, MD, FACS University of Minnesota,Minneapolis,MN |
| 7:40 am – 7:55 am | Concluding Remarks/Rebuttal – Islets |
| 7:55 am – 8:10 am | Concluding Remarks/Rebuttal – Pancreas |
Assessment and Clinical Considerations of New Histocompatibility Tests for Antibody Identification (HLA/Non- HLA) and CrossmatchingChair: Ronald H. Kerman, PhD, University of Texas, Houston, TX and Adriana Zeevi, PhD, University of Pittsburgh, Pittsburgh, PA |
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| 7:00 am – 7:25 am | "Transplant Histocompatibility Conference:" Presentation of the Problems Ronald H. Kerman, PhD University of Texas, Houston, TX |
| 7:25 am – 7:50 am | Antibody Identification, Specificity, the Crossmatch and Clinical Correlations Karen A. Nelson, PhD Puget Sound Blood Center, Seattle,WA |
| 7:50 am – 8:15 am | Involvement of Non-HLA Antigens in Solid Organ Transplantation Elaine F. Reed, PhD University of California, Los Angeles, Los Angeles,CA |
Early Morning Workshops7:00 am – 8:15 am |
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Joint Plenary and Awards8:30 am – 10:00 am |
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State-of-the-Art Address10:00 am – 10:30 amBeyond the T Cell Receptor – Defining Molecular Signaling in Transplantation and Cancer Tak Mak, PhD Princess Margaret Hospital, Toronto, Canada |
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| 10:30 am – 11:00 am | Break |
Concurrent Symposia11:00 am – 12:30 pm |
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Living Donation: A Critical AnalysisChairs: Arthur J. Matas, MD, University of Minnesota, Minneapolis, MN and Robert S. Brown, Jr., MD, MPH, Columbia University, New York, NY*NOTE: This session is a special interactive session with audience response participation |
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| 11:00 am – 11:30 am | Living Donor Follow-Up: Current and Future Regulatory Perspectives Timothy L. Pruett, MD University of Virginia Health Science Center, Charlottesville, VA |
| 11:30 am – 12:00 nn | Living Donor Liver Transplantation: Lessons Learned and Future Direction Kim M. Olthoff, MD University of Pennsylvania, Philadelphia, PA |
| 12:00 nn – 12:30 pm | Living Donor Kidney Transplantation: Defining the Limits Stephen C. Textor, MD Mayo Clinic Rochester, Rochester, MN |
Nanomedicine: Can Tiny Devices Solve Big Problems in Transplantation?Chairs: Anthony M. Jevnikar, MD, London Health Sciences Center, London, Canada and Steven Paraskevas, MD, PhD, McGill University Health Centre, Montreal, Canada |
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| 11:00 am – 11:30 am | Nanotechnology, Nanomolecular Materials and Nanomedicine James R. Baker, MD Michigan Nanotechnology Institute for Medicine and Biological Sciences, Ann Arbor, MI |
| 11:30 am – 12:00 nn | Engineering Novel Diagnostic Modalities and Implantable Cytomimetic Nanomaterials for Next- Generation Medicine Carlo D. Montemagno, PhD, University of Cincinnati, Cincinnati, OH |
| 12:00 nn – 12:30 pm | Nanoparticles to Alter Immune Responses and Battle Cancer Omid C. Farokhzad, MD, Brigham and Women's Hospital, Boston, MA |
Regulatory T Cells and theControl of ImmunityChairs: Wayne W. Hancock, MD, PhD, Children's Hospital of Philadelphia, Philadelphia, PA and David M. Rothstein, MD, Yale Medical School, New Haven, CT |
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| 11:00 am – 11:30 am | FoxP3 in the Control of the Regulatory T Cell Lineage Alexander Rudensky, PhD University of Washington, Seattle,WA |
| 11:30 am – 12:00 nn | The Role of Distinct Subsets of FoxP3+ Regulatory T Cells in the Control of Immune Responses Ethan M. Shevach, MD NIAID/NIH Lab of Immunology,Bethesda, MD |
| 12:00 nn – 12:30 pm | The Connection of TRegs and Th17 Cells Vijay Kuchroo, DVM, PhD, Harvard Medical School, Cambridge, MA |
Modifying Ischemia-Reperfusion Injury for Graft SurvivalChairs: Shaf Keshavjee, MD, Toronto General Hospital, Toronto, Canada and Rutger Ploeg, MD, PhD, University Medical Center Groningen, Groningen, Netherlands |
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| 11:00 am – 11:30 am | Gene Silencing in Preventing IRI: Multi-target Approaches Wei-Ping Min, PhD University Hospital, Ontario, Canada |
| 11:30 am – 12:00 nn | Molecular Profiling of Kidney Ischemia- Reperfusion Hamid Rabb, MD The Johns Hopkins University School of Medicine, Baltimore, MD |
| 12:00 nn – 12:30 pm | Strategies to Prevent IRI in Transplantation:What's New? Jerzy Kupiec-Weglinski, MD, PhD University of California, Los Angeles, Los Angeles, CA |
Industry-supported Satellite Symposia – with lunch12:45 pm – 2:00 pm |
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Concurrent Sessions2:15 pm – 5:00 pm |
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Poster Session II5:00 pm – 6:00 pmwith Beer and Wine Reception |
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Monday, June 2Sunday | Monday | Tuesday | Wednesday |
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Sunrise Symposia7:00 am – 8:15 am |
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Hepatocellular Carcinoma in Liver TransplantationChairs: Elizabeth A. Pomfret, MD, PhD, FACS, Lahey Clinic Medical Center, Burlington, MA and John R. Lake, MD, University of Minnesota, Minneapolis, MN |
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| 7:00 am – 7:25 am | Should Living Donors Be Used For HCC? Robert A. Fisher, MD Medical College of Virginia, Richmond, VA |
| 7:25 am – 7:50 am | Downsizing the Case for Large Tumors Rafik Mark Ghobrial, MD, PhD University of California, Los Angeles, Los Angeles, CA |
| 7:50 am – 8:15 am | Determinants of Recurrence after Transplantation: The Japanese Experience Satoru Todo, MD Hokkaido University School Medical, Sapporo, Japan |
Assessing Cardiovascular Risk Before and After TransplantationChairs: Bertram L. Kasiske, MD, University of Minnesota, Minneapolis, MN and Robert G. Gaston, MD, University of Alabama, Birmingham, AL |
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| 7:00 am – 7:25 am | Pretransplant Screening for Cardiac Disease – Do We Need New Algorithms? Bertram L. Kasiske, MD University of Minnesota, Minneapolis, MN |
| 7:25 am – 7:50 am | Risk Factors for Cardiovascular Mortality Angelo M. De Mattos, MD, MPH University of California – Davis, Sacramento, CA |
| 7:50 am – 8:15 am | Lessons Learned from the ALERT Trial Edward Cole, MD Toronto General Hospital, Toronto, CA |
Innate Immunity in TransplantationChairs: Megan Sykes, MD, Massachusetts General Hospital, Boston, MA and Richard N. Pierson III, MD, University of Maryland-Baltimore, Baltimore, MD |
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| 7:00 am – 7:25 am | Innate Immunity and Evolution of Allorecognition Fadi Lakkis, MD Yale University Medical School, New Haven, CT |
| 7:25 am – 7:50 am | TLR and Innate Immune Activation: Targets for Intervention? Daniel Goldstein, MD Yale University Medical School, New Haven, CT |
| 7:50 am – 8:15 am | Complement and the Innate Immune System Peter S. Heeger, MD Mt. Sinai School of Medicine, New York, NY |
Basic Science of New Therapeutic Targets in Posttransplantation MalignanciesChairs: Anne VanBuskirk, PhD, TAP Pharmaceutical Products, Westerville, OH and Olivia M. Martinez, PhD, Stanford University, Stanford, CA |
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| 7:00 am – 7:25 am | Inflammatory Signaling Pathways in Skin Cancer TBD |
| 7:25 am – 7:50 am | Effects of Gender Differences on Inflammation and Skin Cancer Development Tatiana M. Oberyszyn, PhD Ohio State University, Columbus, OH |
| 7:50 am – 8:15 am | Bench to Bedside: Anti-angiogenesis and Anti-tumor Effects of Immunosuppressants Edward Geissler, PhD University of Regensburg, Wenzenbach, Germany |
Early Morning Workshops7:00 am – 8:15 am |
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Joint Plenary Session8:30 am – 10:00 am |
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Canadian Anniversary Celebration |
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| 10:00 am – 10:30 am | Canadian 50th Anniversary Celebration |
| 10:30 am – 11:00 am | Break |
Concurrent Symposia11:00 am – 12:30 pm |
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Micro RNAi and Control of Lymphocyte DevelopmentChairs: Anita S.F. Chong, PhD, University of Chicago, Chicago, IL and John Iacomini, PhD, Brigham and Women's Hospital, Boston, MA |
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| 11:00 am – 11:30 am | Micro RNAs in Cell Differentiation and Cancer Judy Lieberman, MD, PhD Harvard Medical School, Boston, MA |
| 11:30 am – 12:00 nn | miR-181a Is an Intrinsic Modulator of T Cell Sensitivity and Selection Chang-Zheng Chen, PhD Stanford University, Stanford, CA |
| 12:00 nn – 12:30 pm | Not miR-ly Small RNAs: Big Biological Roles for miRs Carl D. Novina, MD, PhD Dana Farber Cancer Institute, Boston, MA |
Progress in Moving Transplantation Tolerance to the ClinicChairs: Mohamed Sayegh, MD, Brigham and Women's Hospital, Boston, MA and Douglas J. Norman, MD, Oregon Health and Sciences Center, Portland, OR |
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| 11:00 am – 11:30 am | What Are the Hurdles to Achieving Clinical Tolerance: Scientific and Nonscientific? Mohamed Sayegh, MD Brigham and Women's Hospital, Boston, MA |
| 11:30 am – 12:00 nn | Progress on Developing Assays to Measure Tolerance Laurence Turka, PhD University of Pennsylvania, Philadelphia, PA |
| 12:00 nn– 12:30 pm | Review of the Status of All the Clinical Tolerance Protocols Kenneth A. Newell, MD, PhD Emory University, Atlanta, GA |
Pre-emptive Kidney TransplantationChairs: Gabriel M. Danovitch, MD, University of California, Los Angeles, Los Angeles, CA and Michael M. Abecassis, MD, MBA, FRCS, Northwestern University, Chicago, IL |
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| 11:00 am – 11:30 am | Chronic Kidney Disease: Definitions, Risk and Management Bryan N. Becker, MD University of Wisconsin, Madison, WI |
| 11:30 am – 12:00 nn | Making the Case for Pre-emptive Transplantation Robert G. Gaston, MD University of Alabama, Birmingham, AL |
| 12:00 nn – 12:30 pm | Barriers to Pre-Emptive Kidney Transplantation Alan B. Leichtman, MD University of Michigan, Ann Arbor, MI |
Hepatitis C: Are We Really Making Progress?Chairs: Abraham Shaked, MD, PhD, University of Pennsylvania, Philadelphia, PA and Russell H.Wiesner, MD, Mayo Clinic Rochester, Rochester, MN |
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| 11:00 am – 11:30 am | Immunosuppressive Strategies for HCV John R. Lake, MD University of Minnesota, Minneapolis, MN |
| 11:30 am – 12:00 nn | How to Avoid Recurrence in Transplant Recipients Ronald W. Busuttil, MD University of California, Los Angeles, Los Angeles, CA |
| 12:00 nn – 12:30 pm | Novel Therapy in Treatment of HCV Michael R. Charlton, MD Mayo Clinic Rochester, Rochester, MN |
Industry-supported Satellite Symposia – with lunch12:45 pm – 2:00 pm |
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Concurrent Sessions2:15 pm – 5:00 pm |
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Poster Session III5:00 pm – 6:00 pmwith Beer and Wine Reception |
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AST Business Meeting6:00 pm – 7:00 pm |
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Tuesday, June 3Sunday | Monday | Tuesday | Wednesday |
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Sunrise Symposia7:00 am – 8:15 am |
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Update in B-cell ToleranceChairs: Colin Anderson, PhD, Alberta Diabetes Institute,Edmonton, Canada and Marilia I. Cascalho, MD, PhD, Mayo Clinic Rochester, Rochester, MN |
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| 7:00 am – 7:25 am | Control of Immature B-cell Tolerance by Acute and Chronic Exposure to Antigen John C. Cambier, PhD University of Colorado Health Sciences Center, Denver, CO |
| 7:25 am – 7:50 am | Control of the B-cell Intrinsic Tolerance Program by Cbl Ubiquitin Ligases Hua Gu, PhD Columbia University, New York, NY |
| 7:50 am – 8:15 am | Transcriptional Basis of B-cell Tolerance Michael C. Carroll, PhD Harvard Medical School, Boston, MA |
Pediatrics: Are Children Suitable Candidates for Tolerance Regimens?Chairs: George V. Mazariegos, MD, Children's Hospital of Pittsburgh, Pittsburgh, PA and Allan D. Kirk, MD, PhD, Emory University, Atlanta, GA |
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| 7:00 am – 7:25 am | Developmental Aspects of the Immune System and Implications for Tolerance Lori J.West, MD, DPhil University of Alberta, Edmonton, Canada |
| 7:25 am – 7:50 am | Tolerance Induction in Children: Which Strategies Are Most Logical? Joren C. Madsen, MD, DPhil Massachusetts General Hospital, Boston, MA |
| 7:50 am – 8:15 am | The Case for Early Tolerance Induction Studies in Children William E. Harmon, MD Children's Hospital, Harvard Medical School, Boston, MA |
Fellowship Training of the Transplant SpecialistChairs: Donald E. Hricik, MD, University Hospital of Cleveland, Cleveland, OH and Sandy Feng, MD, University of California, San Francisco, San Francisco, CA |
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| 7:00 am – 7:25 am | Educational Paradigms in Transplant Medicine Fuad Shihab, MD University of Utah, Salt Lake City, UT |
| 7:25 am – 7:50 am | Certification of the Transplant Specialist James A. Schulak, MD University Hospitals Case Medical Center, Cleveland, OH |
| 7:50 am – 8:15 am | Training of Fellows in Surgery:Where Are We Today? Goran B. Klintmalm, MD, PhD, FACS Baylor University Health System, Dallas, TX |
Lung Transplantation: Hot TopicsChairs: James S. Allan, MD, Massachusetts General Hospital, Boston, MA and Stuart Sweet, MD, PhD,Washington University, St Louis, MO |
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| 7:00 am – 7:25 am | Assessing Benefit in Lung Transplantation Edward R. Garrity, Jr., MD University of Chicago Hospital, Chicago, IL |
| 7:25 am – 7:50 am | Gastroesophogeal Reflux Disease and Obliterative Bronchiolitis Charles W. Hoopes, MD University of California, San Francisco San Francisco, CA |
| 7:50 am – 8:15 am | Molecular Markers of Lung Injury Shaf Keshavjee, MD University of Toronto, Toronto, Canada |
Early Morning Workshops7:00 am – 8:15 am |
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Joint Plenary and Awards8:30 am – 10:00 am |
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State-of-the-Art Address10:00 am – 10:30 amIssues in the Globalization of Transplantation Luc Noel, World Health Organization, Geneva, Switzerland |
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| 10:30 am – 11:00 am | Break |
Presidential Addresses |
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| 11:00 am – 11:30 am | AST Flavio Vincenti, MD University of California, San Francisco, San Francisco, CA |
| 11:30 am – 12:00 nn | ASTS Goran B. Klintmalm, MD, PhD, FACS Baylor University Medical Center, Dallas, TX |
ASTS and AST Distinguished Service Awards12:00 nn – 12:30 pm |
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Industry-supported Satellite Symposia – with lunch12:45 pm – 2:00 pm |
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Concurrent Sessions2:15 pm – 5:00 pm |
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Poster Session IV5:00 pm – 6:00 pmwith Beer and Wine Reception |
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ASTS Business Meeting6:00 pm – 7:00 pm |
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Wednesday, June 4Sunday | Monday | Tuesday | Wednesday |
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Sunrise Symposia7:00 am – 8:15 am |
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Canadian Perspectives on Clinical TransplantationCo-sponsored by the Canadian Society of Transplantation (CST) and Canadian Institutes of Health Research (CIHR)Chairs: Lori J.West, MD, DPhil, University of Alberta, Edmonton, Canada and Paul A. Keown, MD, PhD, MBA, Vancouver Hospital and HSC, Vancouver, Canada |
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| 7:00 am – 7:25 am | Can We Really Assess Differences in Transplant Outcomes in Canada and the United States? John Gill, MD, MS St. Paul's Hospital, Vancouver, Canada |
| 7:25 am – 7:50 am | Patient and Allograft Survival in Canada: Impact of Racial Diversity and Universal Health Care Sita Gourishankar, MD, MSc University of Alberta, Edmonton, Canada |
| 7:50 am – 8:15 am | Outcomes of Commercial RenalTransplantation: A Canadian Experience Jeffrey Zaltzman, MD St. Michael's Hospital, Toronto, Canada |
Randomized Clinical Trials (RCT's) in Heart TransplantationChairs: Heather J. Ross, MD, Toronto General Hospital, Toronto, Canada and George Tellides, MD, PhD, Yale University School ofMedical, New Haven, CT |
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| 7:00 am – 7:25 am | What Have RCT's Taught Us so Far? Jon Kobashigawa, MD University of California, Los Angeles, Los Angeles, CA |
| 7:25 am – 7:50 am | What Are the Most Important Trials for the Future? Randall C. Starling, MPH Cleveland Clinic, Cleveland, OH |
| 7:50 am – 8:15 am | What Are the Most Important Clinical End-Points For RCT's in 2008? Mandeep R. Mehra, MD University of Maryland, Baltimore, MD |
PolyomavirusChairs: Hans Hirsch, MD, Institute for Medical Microbiology, Basel, Switzerland and Daniel Brennan, MD,Washington University School of Medicine, St. Louis, MO |
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| 7:00 am – 7:25 am | Current Screening and Monitoring Recommendations Parmjeet Randhawa, MD University of Pittsburgh, Pittsburgh, PA |
| 7:25 am – 7:50 am | Leflunomide and Cidofovir – Are They Useful? Michelle A. Josephson, MD University of Chicago, Chicago, IL |
| 7:50 am – 8:15 am | Monitoring Cellular Immune Response to BK Hans H. Hirsch, MD, MSc Institute for Medical Microbiology, Basel, Switzerland |
Living Donor Liver TransplantationChairs: Igal Kam, MD, University of Colorado, Denver, CO, and William Wall, MD, London Health Science Center, London, Canada |
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| 7:00 am – 7:25 am | Living Donor Liver Transplantation: The Asian Experience Chung Mau Lo, MD University of Hong Kong, Hong Kong, China |
| 7:25 am – 7:50 am | Update of the A2ALL Experience (NIH Consortium) Jean C. Emond, MD Columbia University, New York, NY |
| 7:50 am – 8:15 am | Canadian Experience in Adult Living Donor Liver Transplantation David R. Grant, MD Toronto Western Hospital, Toronto, Canada |
Early Morning Workshops7:00 am – 8:15 am |
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Joint Plenary and Awards8:30 am – 10:00 am |
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| 10:00 am – 10:15 am | Break |
Concurrent Symposia11:00 am – 12:30 pm |
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What's Hot, What's New12:00 nn – 1:00 pmBasic: Richard N. Pierson, III, MD Cilinical: R. Mark Ghobrial, MD, PhD |
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